Not had any hard drive failures, but I have never run a PC 24/7 like a server.
I do have a couple of 500GB single platter 7200.12's that I'm keeping an eye on. As mentioned above, the 7200.11 had a firmware issue and the 7200.12 with the 500GB platters seem to have relocated sector counts rising in some cases - probably due to the new 500GB aerial density introduced last year not being refined yet.
My 7200.12's were among the first batch released CC34 firmware I think, with 130MB/s outer speed and 15.2ms access times. Mine both have relocated sectors, but I'm not sure if they came from the factory like that. Keeping an eye on SMART to see if they start to get worse. They are meant to be identical, but one has slightly more sectors that the other (about 2MB's worth). The latest drives have CC44 firmware and 20ms access times I've read - they slowed them down for some reason.
Seagate will replace any drive within its 5 year warranty which is good. I've got some 7200.9 ST3160812A, 160GB single platter, and they are indestructible. Battered them in my main rig and they still never relocated a sector. Now they are in my X-Box's! Use them in my two SFF retro machines too. Nice reliable drives.
Bought some Samsung and a 640GB WD black since the 7200.12's seem a little dodgy - they've all been fine too.



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