The past few days i've been reliving my early computing days by using the 2 MSX emulators on the Amiga. fMSX and AmiMSX. Both of these emulators have their pro's and cons but neither work on graphics cards. If you have a good CPU then i'd recommend fMSX. fMSX is also the most stable of the two and whilst you can open the emulator in a RTG screen it actually slows the emulation down to a snails pace. Most of fMSX settings are accessed via menus opening new windows which can be laborious at times but once you get used to it it's fine. AmiMSX is a faster emulator but is also less acurate and for me was slightly unstable. AmiMSX is slightly easier to configure though. The main reason you may need both emulators is due to some games working on one but not the other. For example Gunfright works fine on fMSX but has corrupted graphics in AmiMSX where as Way of the Tiger is the opposite way round. Ikari Warriors doesn't work on either. Both emulators have cheat modes. If you're looking for a PC MSX emulator then i'd try BlueMSX as it also emulates several other systems.