You definitely need lots of fast ram. I've currently got it setup with all of the KGWHD games totaling 2416 games and it eats up 2MB of fast ram! And I've not added any screenshots to it yet, or sorted any of the games into genres.

Still, if you have a 68030 with at least 8MB fast ram you should be OK. I also expect it would run OK on a standard A1200 with some fast ram, but it could struggle with only 4MB fast ram to leave enough free to actually launch the games.